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Since Federal Air quit flying the route the best you can do is a 1-stop from Nelspruit (Kruger Mpumalanga International Airport) to Vilanculos (VNX). You would fly from Nelspruit to Johannesburg with Airlink and then with LAM Mozambique or Airlink from Johannesburg to Vilanculos.
This route is popular amongst tourists who first want to fly from Johannesburg to Nelspruit to see the wildlife in the Kruger National Park, and then head onwards to Vilanculos to spend time on pristine beaches (although it has become less so since Fedair quit flying the route).
1 December 2012. Fedair quit flying from Nelspruit to Vilanculos (Fedair flight FDR 502 was leaving Nelspruit at 11h15, and arrive at Vilanculos Airport at 13h15, on Tuesdays, Fridays and Saturdays)