Cheap flights from London to South Africa The three major centres of South Africa are Johannesburg, Cape Town and Durban (in that order). There are direct flights from London to Johannesburg, and from London to Cape Town. There are no direct flights from London to Durban, so if your plans are to fly to Durban, first fly from London to Johannesburg (or London to Cape Town), and then catch a local flight from Johannesburg to Durban (or Cape Town to Durban). The links below contain a full list of airlines operating flights on each route and links to their online flight reservation systems.